Now, how much should you take? What is the proper way to administer it? Here’s all you need to know about vitamin D. Vitamin D is one of the most important, the WHO tells us it plays a fundamental role in the correct functioning of the baby’s immune and bone systems. PROSPERO CRD42017073292.Receiving the necessary doses of vitamins is essential for the baby’s growth. Conclusion: vitamin D supplementation during pregnancy improves serum 25 (OH) D concentration and suggests positive effects on overall health condition, length at birth and birth weight. Significant effects were also presented at the length at birth considering any supplemented dose (MD=0.19 CI95%=0.08-0.30 p=0.0010 I2=0%, 1452 participants, low quality evidence) and birth weight in doses higher than 4000IU/day (MD=257.05 (CI95%=137.81-376.29 p<0.0001 I2=14%, 176 participants, moderate quality evidence). Results: the newborn’s overall health condition was presented as Apgar, with a mean difference (MD) of 0.15 (CI95%=0.06-0.25 p=0.002 I2=0%, two studies, 648 participants, moderate quality evidence) at the first minute and 0.11 (CI95%=0.04-0.17 p=0.001 I2=0%, two studies, 648 participants, moderate quality evidence) at the fifth minute. The data was analyzed on RevMan 5.4 software and the quality of evidence on GRADE. Randomized controlled trials were searched by evaluating the effects of maternal vitamin D supplementation in neonates. Methods: this research was conducted in the electronic databases of MEDLINE, LILACS, EMBASE and Cochrane Library until December 2020, using the terms “vitamin D”, “pregnancy”, “vitamin D deficiency”, “infant”, “newborn” and their synonyms. Abstract Objectives: to assess the effects of vitamin D supplementation during pregnancy on the outcomes of vitamin D concentration in newborns, length at birth, overall health (Apgar), birth weight and maternal vitamin D concentration after childbirth.
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